Protini™ Polypeptide Cream

A peptide-heavy moisturizer with solid encapsulation technology and optimal pH, but efficacy is undermined by unclear peptide concentrations and reliance on unproven growth factor claims. The formula scores well for its sophisticated delivery system—the Copper Palmitoyl Heptapeptide-14 is wrapped in a biocompatible polymer capsule (Lactic Acid/Glycolic Acid Copolymer) designed to target fibroblasts, which is genuinely innovative[1]. The pH of 4.0 is skin-friendly and appropriate for peptide stability[2]. However, the efficacy score is capped at 3.6 because: (1) peptide concentrations are not disclosed—they appear mid-to-late in the INCI list, suggesting modest levels that may not deliver clinically meaningful collagen stimulation[1]; (2) the BIO-Placenta growth factor complex lacks robust clinical evidence for topical efficacy in cosmetic formulations[1]; (3) the formula relies heavily on marketing language ("signal peptides," "growth factors") without transparent substantiation; (4) while Sodium Hyaluronate and Glycerin provide hydration, this is a moisturizer first and an anti-aging treatment second; (5) the amino acid blend, though comprehensive, is likely present in trace amounts given their position in the INCI list. The encapsulation technology is genuinely impressive and elevates this above a basic peptide moisturizer, but the lack of concentration transparency and unproven growth factor claims prevent a higher score. If you're looking for skincare anti aging products or vegan skincare, this is worth evaluating.

This is a fragrance free skincare formula, making it suitable as fragrance free skincare for sensitive skin. No Tier 1 Gold Standard actives were detected. Potential irritants found: Phenoxyethanol, Chlorphenesin.

Drunk Elephant Protini™ Polypeptide Cream has a safety score of 4.7/5. It contains potential irritants including Phenoxyethanol, Chlorphenesin. Patch testing is recommended. As a fragrance free moisturiser suitable for sensitive skin care, it avoids common triggers for reactivity.

Based on its formulation, Drunk Elephant Protini™ Polypeptide Cream is best suited as a moisturizer for sensitive skin.

DemythSkin recommends: The Ordinary Buffet + Copper Peptides 1% — Delivers transparent peptide concentrations (1% copper peptides) at a fraction of the cost. While lacking the sophisticated encapsulation of Protini, it offers better value for peptide-seeking consumers and includes a broader amino acid complex.. Olay Regenerist Micro-Sculpting Cream — Clinically proven peptide moisturizer with transparent formulation, retinol derivative, and hyaluronic acid at a significantly lower price point. Offers better documented efficacy for fine lines and firmness.. Augustinus Bader The Rich Cream — Premium peptide-based moisturizer with proprietary TFC8 complex and transparent clinical backing. Comparable price to Protini but with stronger evidence-based formulation and better ingredient synergy..

Drunk Elephant Protini™ Polypeptide Cream is marketed with anti-aging claims. Our analysis scores it 3.6/5 for efficacy — check the Tier 1 ingredients above to evaluate whether it delivers on its skincare anti aging products claims.

Based on DemythSkin's INCI analysis, no fragrance, parfum, or essential oils were detected in Drunk Elephant Protini™ Polypeptide Cream's formula. This makes it a strong candidate as a fragrance free moisturiser for dry skin or fragrance free skincare for sensitive skin care routines. Always cross-check the current label as formulas can change.

DemythSkin uses a 5-tier clinical ingredient system to score every product from 0–5 on both Efficacy and Safety. Tier 1 is Gold Standard actives with high clinical proof. Tier 5 flags potential irritants like fragrance, drying alcohols, and essential oils. Scores power our skincare routine for glow up database — helping you find the best anti aging moisturizer, best sunscreen for sensitive skin, or fragrance free skincare without the marketing noise.